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1.
J Biol Dyn ; 16(1): 619-639, 2022 12.
Article in English | MEDLINE | ID: covidwho-2187649

ABSTRACT

In this paper, we are concerned with an epidemic model with quarantine and distributed time delay. We define the basic reproduction number R0 and show that if R0≤1, then the disease-free equilibrium is globally asymptotically stable, whereas if R0>1, then it is unstable and there exists a unique endemic equilibrium. We obtain sufficient conditions for a Hopf bifurcation that induces a nontrivial periodic solution which represents recurrent epidemic waves. By numerical simulations, we illustrate stability and instability parameter regions. Our results suggest that the quarantine and time delay play important roles in the occurrence of recurrent epidemic waves.


Subject(s)
Epidemics , Quarantine , Basic Reproduction Number , Computer Simulation , Models, Biological
2.
J Biol Dyn ; 15(1): 342-366, 2021 12.
Article in English | MEDLINE | ID: covidwho-1286516

ABSTRACT

We propose two models inspired by the COVID-19 pandemic: a coupled disease-human behaviour (or disease-game theoretic), and a coupled disease-human behaviour-economic model, both of which account for the impact of social-distancing on disease control and economic growth. The models exhibit rich dynamical behaviour including multistable equilibria, a backward bifurcation, and sustained bounded periodic oscillations. Analyses of the first model suggests that the disease can be eliminated if everybody practices full social-distancing, but the most likely outcome is some level of disease coupled with some level of social-distancing. The same outcome is observed with the second model when the economy is weaker than the social norms to follow health directives. However, if the economy is stronger, it can support some level of social-distancing that can lead to disease elimination.


Subject(s)
Communicable Diseases, Emerging/epidemiology , Game Theory , Pandemics/economics , Physical Distancing , COVID-19 , Humans
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